The perspectives on the FDA new approvals in 2018 have started to appear but I doubt any will look back to the discovery origins of these drugs. So here goes with some "where did they come from" information distilled from the initial patent filings on the chemical structures.
From the inventor addresses and the original assignments, most were invented on the east or west coast of the US, distributed as shown in the map.
Notable, the absence of inventions from the UK and only one from Germany, and that's lofexidine from 1967 when it was patented for the treatment of hypertension.
Some echoes from the past with drugs invented at Syntex (segesterone acetate), American Cyanamid (moxidectin) and Warner-Lambert (dacomitinib).